Occasional Revziew Bromocriptine in Parkinsonism
نویسنده
چکیده
A review of the effects of using bromocriptine in Parkinson's disease showed that it rarely helps patients not primarily improved by levodopa. Patients who show late failure with levodopa and whose response to treatment is declining are helped by combining the two drugs. High cost and severe psychosis are the main disadvantages of bromocriptine, and, although it is not recommended for patients who are doing well on levodopa, it is the best available drug for hospital use in patients who show late failure with levodopa.
منابع مشابه
Bromocriptine in Parkinsonism: long-term treatment, dose response, and comparison with levodopa.
Thirty-seven patients with Parkinsonism were treated with bromocriptine 2.5-300 mg daily. Bromocriptine, alone or combined with levodopa, caused a 20-30% reduction in disability scores in 11 patients treated for one year. Tolerance did not develop during this period. Bromocriptine treatment was not of value in six patients who had previously not responded or who had lost their response to levod...
متن کاملBromocriptine in parkinsonism.
A review of the effects of using bromocriptine in Parkinson's disease showed that it rarely helps patients not primarily improved by levodopa. Patients who show late failure with levadopa and whose response to treatment is declining are helped by combining the two drugs. High cost and severe psychosis are the main disadvantages of bromocriptine, and, although it is not recommended for patients ...
متن کاملBromocriptine-induced psychosis in acromegaly.
Dopaminergic mechanisms have been implicated in the pathogenesis of schizophrenia.' Psychosis induced by the dopamine-receptor agonist bromocriptine has been described mainly with high-dose regimens in Parkinsonism and less frequently with the lower doses used in hormonal disorders.24 The following case is of interest because of the insidious onset of psychosis and the family history of paranoi...
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متن کاملLong-term treatment of Parkinson's disease with bromocriptine.
BRomocriptine (15-75 mg per day) alone or with L-dopa was studied during five to 29 months on 44 patients with Parkinson's disease. Used as sole therapeutic agent, it was found excellent in 12 patients who had never received regular L-dopa treatment either because it was never attempted or because of intolerance from the outset. Its anti-Parkinsonism activity was comparable with L-dopa. The gai...
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تاریخ انتشار 2006